About Sho-saiko-to

Sho-Saiko-To (SST), also known as Minor Bupleurum Formula and Xiao Chai Hu Tang in Chinese, is a supplement used to aid in liver function based upon Kampo, the Japanese adaptation of traditional Chinese medicine. It is comprised of 7 herbal ingredients (Bupleurum Root, Pinellia Tuber, Scutellaria Root, Ginseng, Jujube, Licorice, and Ginger) that work synergistically to aid in liver health. SST is currently undergoing clinical trial at Memorial Sloan-Kettering Cancer Center in New York and the Liver Center at University of California San Diego.

 

Honso Sho-saiko-to

(The Only Standardized Japanese Herbal Remedy for Liver Health*)
  
 

Sho-saiko-to (SST or Liver Kampo, Honso's consumer product) is a classic Chinese botanical formulation widely known by its Japanese name.

MAY HELP

  • To improve liver function*
  • To increase immune against harmful damages on the body*
  • To enhance digestive health*

CONSTITUENTS

Sho-saiko-to is a mixture of seven botanicals:

  • Bupleurum root (Chai hu)
  • Pinellia tuber (Ban xia)
  • Scutellaria root (Huang qin)
  • Ginseng (Ren shen)
  • Jujube (Da zao)
  • Licorice (Gan cao)
  • Ginger (Sheng jiang)

A number of pharmacologically active components have been isolated including:

  • Baicalin
  • Baicalein
  • Glycyrrhizin
  • Saikosaponins
  • Ginsenosides 
  • Wogonin
  • Gingerols

The standardization specification (HPLC assay) by Honso Pharmaceutical Co., Ltd.:.(4)

  • Glycyrrhizin: 24.7-46.0 mg/day
  • Baicalin: 110.6-205.6 mg/day
  • Saikosaponin: 6.5-19.7 mg/day

PHARMACOKINETICS

Due to the complexity of this formula, only limited data is available. One study indicates that the serum concentration of glycyrrhizin after a normal daily dose is 1.2 mcg/ml.

WARNINGS

Sho-saiko-to may cause interstitial pneumonitis, a potentially fatal condition. Concurrent use of interferon may increase this risk.

CONTRAINDICATIONS

Women who are nursing or pregnant and patients currently undergoing interferon treatment should not take Sho-saiko-to.

*The information provided here is for healthcare professional practitioners only. This product is a "traditional Asian medicine" formula. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

  

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About Sho-saiko-to